antibody

CD33 Antibody (clone WM53) LS-C357759

LS-C357759

monoclonal

mouse

nonconjugated

WM53

The same clone is also sold as:

• BD Biosciences: 561816, 562854, 562492, 555449, 555450, 551378, 561157, 561817, 551377
• Bio-Rad: MCA1271, MCA1271APC, MCA1271SBUV795, MCA1271AMO, MCA1271SBV515, MCA1271PE, MCA1271SBV570, MCA1271SBUV510, MCA1271SBV670, MCA1271F, MCA1271T, MCA1271A700T, MCA1271SBV475, MCA1271A488, MCA1271A647, MCA1271SBUV400, MCA1271SBB700, MCA1271SBUV665, MCA1271SBV610, MCA1271SBV440, MCA1271GA, MCA1271SBV790, MCA1271SBV710, MCA1271A647T, MCA1271A700
• Exbio: T9-662-T100, PC-662-T025, PC-662-T100, 1F-662-T100, 11-662-C100, 12-662-C100, T9-662-T025, 1P-662-T100, 1A-662-T100, T4-662-T025, 11-662-C025, 1P-662-T025, T7-662-T100, 1A-662-T025, A7-662-T025, 1F-662-T025, A7-662-T100, T8-662-T025, T4-662-T100, T8-662-T100
• OriGene: SM1103R, SM1103APC, SM1103F, SM1103P, SM1103PT, SM1103PS
• BioLegend: 303402, 303430, 303436, 303419, 303406, 983904, 303438, 303437, 303432, 303440, 303428, 303424, 303441, 303434, 303431, 303416, 303426, 303421, 303415, 303429, 303408, 303403, 303422, 303404, 983908, 983902, 303413, 303423, 303433, 303442, 303435, 983906, 303427, 260130, 303417, 303414, 303439, 303407
• Invitrogen: MA5-18056, MA5-16982, MA5-16981, MA1-33439, A15763, A15727, A15795, A15804, A15454, MA5-16980
• Abcam: ab206634, ab234216, ab213050
• Novus Biologicals: NBP3-09095
• ImmuQuest: IQ473

immunocytochemistry, flow cytometry

LS-C357759

Human

Mouse

CD33 Antibody (clone WM53) LS-C357759

Human CD33

Monoclonal

WM53

Unconjugated

1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide

Cells

Human AML cells were used as the immunogen for this CD33 antibody.

Protein G purified

Store at 2°C to 8°C.

IgG1,k

CD33

CD33

Immunoglobulin

Human

Flo (0.5 - 1 µg/10E6 cells), Func, IF (0.5 - 1 µg/ml)

CD33 antibody LS-C357759 is an unconjugated mouse monoclonal antibody to human CD33. Validated for Flow, Func and IF.

This antibody recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV. WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies. these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells. ELISA: Order BSA-free antibody format for coating.

CD33, CD33 antigen, CD33 molecule, gp67, SIGLEC-3, p67, CD33 antigen (gp67), SIGLEC3

Worldwide