This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CD1A Antibody (clone O10 + C1A/711) LS-C357745
catalog :
LS-C357745
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
O10 + C1A/711
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
product information
AntibodyID :
369290
AntibodyName :
LS-C357745
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
CD1A Antibody (clone O10 + C1A/711) LS-C357745
Specificity :
Human CD1A
ClonalityDesc :
Monoclonal
CloneName :
O10 + C1A/711
AntibodyModification :
Unconjugated
PresentationDesc :
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Human thymus cells (O10) and recombinant human CD1a protein (C1A/711)l.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
IsotypeName :
IgG1,k
Gene :
CD1A
StandardGeneSymbol :
CD1A
Reactivity :
Human
Usage :
Flo (0.5 - 1 µg/10E6 cells), IF (1 - 2 µg/ml), IHC, IHC-P (0.5 - 1 µg/ml), IP, WB (0.5 - 1 µg/ml)
ShortWebDescription :
CD1A antibody LS-C357745 is an unconjugated mouse monoclonal antibody to human CD1A. Validated for Flow, IF, IHC, IP and WB.
UsageText :
At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. CD1a antibody labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibody against TTF-1 and CD5, CD1a antibody is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. antibody to CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).
Synonyms :
CD1A, CD1, CD1A antigen, a polypeptide, CD1a molecule, FCB6, HTA1, HTa1 thymocyte antigen, R4, T6, CD1a antigen, Cluster of differentiation 1 A
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.