This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
BCL2 / Bcl-2 Antibody (aa41-54, clone 8C8) LS-C357723
catalog :
LS-C357723
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
8C8

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
product information
AntibodyID :
369268
AntibodyName :
LS-C357723
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
BCL2 / Bcl-2 Antibody (aa41-54, clone 8C8) LS-C357723
Specificity :
Human BCL2 / Bcl-2
ClonalityDesc :
Monoclonal
CloneName :
8C8
AntibodyModification :
Unconjugated
AntigenModification :
aa41-54
PresentationDesc :
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A synthetic peptide, aa 41-54 (G aa PAPGIFSSQPG-Cys) of human Bcl-2 protein. Percent identity by BLAST analysis: Human, Chimpanzee, Cat, Pig, Dog (100%); Gorilla, Orangutan, Bovine, Goat (91%); Galago (82%).
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
IsotypeName :
IgG1,k
Gene :
BCL2 / Bcl-2
StandardGeneSymbol :
BCL2
gene family :
Apoptosis
Reactivity :
Dog, Pig, Human, Monkey, Chimpanzee
NonReactiveSpecies :
Mouse, Rat
Usage :
ELISA, Flo (0.5 - 1 µg/10E6 cells), IF (1 - 2 µg/ml), IHC, IHC-P (0.5 - 1 µg/ml), IP, WB (0.5 - 1 µg/ml)
ShortWebDescription :
Bcl-2 antibody LS-C357723 is an unconjugated mouse monoclonal antibody to Bcl-2 (BCL2) (aa41-54) from human. It is reactive with human, chimpanzee, dog and other species. Validated for ELISA, Flow, IF, IHC, IP and WB.
UsageText :
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 alpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 alpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative. ELISA: Order BSA-free format for coating.
Synonyms :
BCL2, Apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, B-cell lymphoma protein 2, Bcl-2, PPP1R50
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.