This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
APG4B / ATG4B Antibody (C-Terminus) LS-C357715
catalog :
LS-C357715
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
product information
AntibodyID :
369260
AntibodyName :
LS-C357715
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
APG4B / ATG4B Antibody (C-Terminus) LS-C357715
Specificity :
Human APG4B / ATG4B
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
C-Terminus
PresentationDesc :
1X PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
A recombinant protein fragment from the C-Terminus of ATG4B.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG
Gene :
APG4B / ATG4B
StandardGeneSymbol :
ATG4B
Reactivity :
Mouse, Human
Usage :
WB (4 - 8 µg/ml)
ShortWebDescription :
ATG4B antibody LS-C357715 is an unconjugated rabbit polyclonal antibody to ATG4B (APG4B) (C-Terminus) from human. It is reactive with human and mouse. Validated for WB.
UsageText :
Autophagy is the cellular mechanism of degradation and turnover of unnecessary or dysfunctional cellular components. The unneeded components are engulfed in vesicles called autophagosomes, where they are broken down and recycled. The [Character 91]autophagy-related gene' ATG4B is a regulator of autophagasome maturation. The microtubule-associated protein LC3-I is lipidated (called LC3-II in its lipidated state) and recruited to the autophagosomal membrane where it is of vital importance in the maturation of autophagosomes. ATG4B regulates LC3-II availability by modulating LC3-I lipidation.
Synonyms :
ATG4B, APG4 autophagy 4 homolog B, AUTL1, Autophagin-1, Cysteine protease ATG4B, HAPG4B, APG4B, KIAA0943
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.