This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
SFN / Stratifin / 14-3-3 Sigma Antibody (Internal) LS-C357707
catalog :
LS-C357707
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
product information
AntibodyID :
369252
AntibodyName :
LS-C357707
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
SFN / Stratifin / 14-3-3 Sigma Antibody (Internal) LS-C357707
Specificity :
Human SFN / Stratifin / 14-3-3 Sigma
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
Internal
PresentationDesc :
1X PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
A recombinant protein fragment from the internal region of 14-3-3 sigma.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG
Gene :
SFN / Stratifin / 14-3-3 Sigma
StandardGeneSymbol :
SFN
Reactivity :
Mouse, Rat, Human
Usage :
WB (1 - 3 µg/ml)
ShortWebDescription :
14-3-3 Sigma antibody LS-C357707 is an unconjugated rabbit polyclonal antibody to 14-3-3 Sigma (SFN / Stratifin) (Internal) from human. It is reactive with human, mouse and rat. Validated for WB.
UsageText :
14-3-3 proteins are regulators of a diverse group of signaling proteins, including kinases, phosphatases, and transmembrane receptors, and have roles in a wide range of physiological processes including transcription, intracellular signaling, cell cycle control and apoptosis. There are seven 14-3-3 proteins in most mammals: beta, gamma epsilon, zeta, eta, sigma and tau. 14-3-3 sigma, also called Stratifin, is a product of the SFN gene. It is a tumor suppressor gene inactivated via DNA methylation. Reduced or no expression of 14-3-3 sigma is seen in various carcinoma including skin, breast and prostate, suggesting that 14-3-3 gene silencing may be involved in tumor progression.
Synonyms :
SFN, 14-3-3 sigma, 14-3-3 protein sigma, HME1, Stratifin, YWHAS
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.