product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
ACTC1 / Alpha Cardiac Actin Antibody (N-Terminus) LS-C34835
catalog :
LS-C34835
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 1
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:200
Itier J, Ret G, Viale S, Sweet L, Bangari D, Caron A, et al. Effective clearance of GL-3 in a human iPSC-derived cardiomyocyte model of Fabry disease. J Inherit Metab Dis. 2014;37:1013-22 pubmed publisher
product information
AntibodyID :
34341
AntibodyName :
LS-C34835
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
ACTC1 / Alpha Cardiac Actin Antibody (N-Terminus) LS-C34835
Specificity :
Recognizes fetal cardiac actin. Represents an excellent marker for cardiac tissue; it discriminates fetal (cardiac) a-actin from all other actin isoforms. Shows no cross-reaction with other actin isoforms present in skeletal and smooth muscle, provided that stringent experimental conditions have been applied. Species cross-reactivity: Human, bovine, rabbit, chicken.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
AntigenModification :
N-Terminus
PresentationDesc :
Lyophilized PBS, pH 7.4, 0.09% Sodium Azide, 0.5% BSA
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic N-Terminus decapeptide of cardiac isoform of actin.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Reconstituted or lyophilized: store at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid freeze-thaw cycles.
ResuspensionLiquidDesc :
sterile ddH2O.
IsotypeName :
IgG1
Gene :
ACTC1 / Alpha Cardiac Actin
StandardGeneSymbol :
ACTC1
Reactivity :
Chicken, Bovine, Rabbit, Human
Usage :
ELISA (1:500), IHC, IHC-Fr, IHC-P, WB (1:1000)
ShortWebDescription :
Alpha Cardiac Actin antibody LS-C34835 is an unconjugated mouse monoclonal antibody to Alpha Cardiac Actin (ACTC1) (N-Terminus) from human. It is reactive with human, bovine, chicken and other species. Validated for ELISA, IHC and WB.
UsageText :
Suitable for use in Western Blot, ELISA and Immunohistochemistry. Immunohistochemistry: 1:10. Frozen and paraffin sections. Note: It is necessary to include 0.5 M sodium chloride in all washing buffers for application on frozen tissue. This is not necessary for paraffin sections. Western Blot: 1:1000 (using the ECL-enhanced procedure). ELISA: 1:500. Note: It is necessary to include 1 M sodium chloride for application in Western blot and ELISA to enhance specificity.
Synonyms :
ACTC1, Actin, alpha cardiac muscle 1, Actin, alpha, cardiac muscle, Actin, alpha, cardiac muscle 1, Alpha-cardiac actin, CMH11, CMD1R, ACTC, LVNC4, ASD5
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.