This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
VCAM1 / CD106 Antibody (clone B-K9) LS-C347455
catalog :
LS-C347455
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
reactivity :
human
application :
flow cytometry
product information
AntibodyID :
358412
AntibodyName :
LS-C347455
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
VCAM1 / CD106 Antibody (clone B-K9) LS-C347455
Specificity :
Human CD106
ClonalityDesc :
Monoclonal
CloneName :
B-K9
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Cells
ImmunogenDesc :
B-K9 is a mouse monoclonal IgG1 antibody derived by fusion of X63/Ag8.653 mouse myeloma cells with spleen cells from BALB/c mice immunized with activated human umbilical vein endothelial cells.
PurificationDesc :
Purified
RecommendedStorageDesc :
Store at 4°C, or in small aliquots at -20°C.
IsotypeName :
IgG1
Gene :
VCAM1 / CD106
StandardGeneSymbol :
VCAM1
gene family :
ICAM
Reactivity :
Human
Usage :
Flo
ShortWebDescription :
CD106 antibody LS-C347455 is an unconjugated mouse monoclonal antibody to human CD106 (VCAM1). Validated for Flow.
UsageText :
CD106 is a 110kD type 1 transmembrane sialoglycoprotein, which is also known as vascular cell adhesion molecule 1 (VCAM-1). The CD106 protein is primarily expressed on activated vascular endothelium but has also been detected on dendritic cell types, macrophages and non-vascular cells in certain tissues. Expression of CD106 is induced by inflammatory stimuli and cytokines. CD106 binds to the integrins CD49d/CD29 (also known as VLA4) and alpha4beta7 and is important in leucocyte-endothelial cell adhesion and signal transduction. The CD106 protein is thought to play a key role in the migration of leucocyte from the blood into tissues, particularly at sites of inflammation. Studies suggest that CD106 may also play a role in the development of rheumatoid arthritis and atherosclerosis.
Synonyms :
VCAM1, CD106, CD106 antigen, INCAM-100, V-CAM 1, VCAM-1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.
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