This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
ICAM3 / CD50 Antibody (clone JA4) LS-C346819
catalog :
LS-C346819
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
JA4

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry
product information
AntibodyID :
357776
AntibodyName :
LS-C346819
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
ICAM3 / CD50 Antibody (clone JA4) LS-C346819
Specificity :
A linear epitope in domains 1 and 2 of ICAM-3.
ClonalityDesc :
Monoclonal
CloneName :
JA4
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Cells
ImmunogenDesc :
JA4 is a mouse monoclonal IgG1/k antibody derived by fusion of mouse Ag8.653 cells with spleen cells from a BALB/c mouse immunized with an ICAM-3/HEK transfectant.
PurificationDesc :
Purified
RecommendedStorageDesc :
Store at 4°C, or in small aliquots at -20°C.
IsotypeName :
IgG1
Gene :
ICAM3 / CD50
StandardGeneSymbol :
ICAM3
gene family :
ICAM
Reactivity :
Human
Usage :
ELISA, Flo, ICC, IP, WB
ShortWebDescription :
CD50 antibody LS-C346819 is an unconjugated mouse monoclonal antibody to human CD50 (ICAM3). Validated for ELISA, Flow, ICC, IP and WB.
UsageText :
Intercellular adhesion molecule 3 (ICAM3) also known as CD50 (Cluster of Differentiation 50), is a type I transmembrane glycoprotein, which normally contain 2-9 immunoglobulin-like C2-type domains, and binds to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. ICAM-3 has previously been implicated in apoptotic cell clearance, although its precise role in the clearance process is ill defined.
Synonyms :
ICAM3, CD50, CDW50, ICAM-R, CD50 antigen, ICAM-3
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.