product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
CTLA4 / CD152 Antibody (clone A3.4H2.H12) LS-C34558
catalog :
LS-C34558
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
A3.4H2.H12
reactivity :
human
application :
ELISA, flow cytometry
citations: 3
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
  • ELISA; human
Norström M, Rådestad E, Sundberg B, Mattsson J, Henningsohn L, Levitsky V, et al. Progression of benign prostatic hyperplasia is associated with pro-inflammatory mediators and chronic activation of prostate-infiltrating lymphocytes. Oncotarget. 2016;7:23581-93 pubmed publisher
Rådestad E, Sundin M, Törlén J, Thunberg S, Önfelt B, Ljungman P, et al. Individualization of Hematopoietic Stem Cell Transplantation Using Alpha/Beta T-Cell Depletion. Front Immunol. 2019;10:189 pubmed publisher
Matsuzawa T, Ogawa Y, Moriishi K, Shimada S, Kawamura T. Immunological function of Langerhans cells in HIV infection. J Dermatol Sci. 2017;87:159-167 pubmed publisher
product information
AntibodyID :
33601
AntibodyName :
LS-C34558
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
CTLA4 / CD152 Antibody (clone A3.4H2.H12) LS-C34558
Specificity :
Human CTLA-4 (also known as Cytotoxic T lymphocyte-associated antigen-4, CD152) is a structural homologue of T cell co-stimulatory receptor CD28. CTLA-4 binds to the same ligands (CD80 and CD86) as CD28 but with much higher avidity. It is expressed at very low levels on the cell surface of activated T cells, and is found primarily in the post-Golgi or endosomal compartments of the cell.
ClonalityDesc :
Monoclonal
CloneName :
A3.4H2.H12
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.02% Sodium Azide
ImmunogenDesc :
Activated T cells.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
IsotypeName :
IgG2a,k
Gene :
CTLA4 / CD152
StandardGeneSymbol :
CTLA4
Reactivity :
Human
Usage :
Flo (1 µg/10E6 cells)
UsageNotRecommended :
IHC-P
ShortWebDescription :
CD152 antibody LS-C34558 is an unconjugated mouse monoclonal antibody to human CD152 (CTLA4). Validated for Flow. Cited in 3 publications.
Synonyms :
CTLA4, CD152, CELIAC3, CD152 antigen, CTLA-4, Celiac disease 3, IDDM12, GRD4, GSE, CD152 isoform
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.