product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
LAG3 Antibody (aa70-99, clone 17B4) LS-C344932
catalog :
LS-C344932
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
17B4
reactivity :
human
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:100; fig 2
Chen P, Roh W, Reuben A, Cooper Z, Spencer C, Prieto P, et al. Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade. Cancer Discov. 2016;6:827-37 pubmed publisher
Crane G, Samols M, Morsberger L, Yonescu R, Thiess M, Batista D, et al. Tumor-Infiltrating Macrophages in Post-Transplant, Relapsed Classical Hodgkin Lymphoma Are Donor-Derived. PLoS ONE. 2016;11:e0163559 pubmed publisher
product information
AntibodyID :
355815
AntibodyName :
LS-C344932
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
LAG3 Antibody (aa70-99, clone 17B4) LS-C344932
Specificity :
Recognizes the 30 aa extra-loop of the first N-terminal D1 domain of human LAG-3.
ClonalityDesc :
Monoclonal
CloneName :
17B4
AntibodyModification :
Unconjugated
AntigenModification :
aa70-99
PresentationDesc :
PBS, 0.02% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to 30 aa (GPPAAAPGHPLAPGPHPAAPSSWGPRPRRY) from the first N-Terminus D1 domain of human LAG-3 (lymphocyte activation gene-3). Percent identity by BLAST analysis: Human (100%); Gorilla (93%); Gibbon (90%); Monkey (83%).
PurificationDesc :
Protein G purified from tissue culture supernatant
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1,k
Gene :
LAG3
StandardGeneSymbol :
LAG3
Reactivity :
Human
Usage :
Func, ICC, IHC-P (10 µg/ml), WB (5 µg/ml)
ShortWebDescription :
LAG3 antibody LS-C344932 is an unconjugated mouse monoclonal antibody to human LAG3 (aa70-99). Validated for Func, ICC, IHC and WB.
UsageText :
Functional Application - Inhibition. Immunohistochemistry - Frozen sections 1:150.
Synonyms :
LAG3, CD223 antigen, LAG-3, Protein FDC, CD223, FDC, Lymphocyte-activation gene 3
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.