product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
PTGS2 / COX2 / COX-2 Antibody (aa18-260, clone OTI5F12) LS-C339530
catalog :
LS-C339530
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OTI5F12
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section, blocking or activating experiments
citations: 2
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; human; 10 ug/ml
Montagner I, Merlo A, Zuccolotto G, Renier D, Campisi M, Pasut G, et al. Peritoneal tumor carcinomatosis: pharmacological targeting with hyaluronan-based bioconjugates overcomes therapeutic indications of current drugs. PLoS ONE. 2014;9:e112240 pubmed publisher
Montagner I, Banzato A, Zuccolotto G, Renier D, Campisi M, Bassi P, et al. Paclitaxel-hyaluronan hydrosoluble bioconjugate: mechanism of action in human bladder cancer cell lines. Urol Oncol. 2013;31:1261-9 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-C339530 image 1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTGS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PTGS2.
image 2 :
LifeSpan Biosciences LS-C339530 image 2
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PTGS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
product information
AntibodyID :
350141
AntibodyName :
LS-C339530
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PTGS2 / COX2 / COX-2 Antibody (aa18-260, clone OTI5F12) LS-C339530
Specificity :
Human PTGS2 / COX2 / COX-2
ClonalityDesc :
Monoclonal
CloneName :
OTI5F12
AntibodyModification :
Unconjugated
AntigenModification :
aa18-260
PresentationDesc :
PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol, 1% BSA
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Human recombinant protein fragment corresponding to amino acids 18-260 of human PTGS2 (NP_000954) produced in E. coli.
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG2b
Gene :
PTGS2 / COX2 / COX-2
StandardGeneSymbol :
PTGS2
Reactivity :
Human
Usage :
IHC, IHC-P (1:150), WB (1:2000)
ShortWebDescription :
COX-2 antibody LS-C339530 is an unconjugated mouse monoclonal antibody to human COX-2 (PTGS2 / COX2) (aa18-260). Validated for IHC and WB.
Synonyms :
PTGS2, COX-2, Cyclooxygenase-2, COX2, Cyclooxygenase 2b, HCox-2, GRIPGHS, PGH synthase 2, PGHS-2, PHS II, PHS-2, Prostaglandin H2 synthase 2, PGG/HS, Prostaglandin G/H synthase 2
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.