product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
RIPK3 / RIP3 Antibody (aa233-518, clone OTI2F12) LS-C336804
catalog :
LS-C336804
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OTI2F12
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
citations: 1
Reference
Li D, Chen J, Guo J, Li L, Cai G, Chen S, et al. A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes prostaglandin2α-induced corpus luteum regression. elife. 2021;10: pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-C336804 image 1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RIPK3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RIPK3.
image 2 :
LifeSpan Biosciences LS-C336804 image 2
IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-RIPK3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
product information
AntibodyID :
347415
AntibodyName :
LS-C336804
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
RIPK3 / RIP3 Antibody (aa233-518, clone OTI2F12) LS-C336804
Specificity :
Human RIPK3 / RIP3
ClonalityDesc :
Monoclonal
CloneName :
OTI2F12
AntibodyModification :
Unconjugated
AntigenModification :
aa233-518
PresentationDesc :
PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol, 1% BSA
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Human recombinant protein fragment corresponding to amino acids 233-518 of human RIPK3 (NP_006862) produced in E. coli.
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
RIPK3 / RIP3
StandardGeneSymbol :
RIPK3
gene family :
Protein Kinase
Subfamily :
RIP
Reactivity :
Human
Usage :
IHC, IHC-P (1:150), WB (1:2000)
ShortWebDescription :
RIP3 antibody LS-C336804 is an unconjugated mouse monoclonal antibody to human RIP3 (RIPK3) (aa233-518). Validated for IHC and WB. Cited in 1 publication.
Synonyms :
RIPK3, Receptor interacting protein 3, RIP-like protein kinase 3, RIP3, RIP-3, Receptor-interacting protein 3
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.