product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
HSPB1 / HSP27 Antibody (C-Terminus) LS-C31836
catalog :
LS-C31836
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human
Booth L, Roberts J, Sander C, Lee J, Kirkwood J, Poklepovic A, et al. The HDAC inhibitor AR42 interacts with pazopanib to kill trametinib/dabrafenib-resistant melanoma cells in vitro and in vivo. Oncotarget. 2017;8:16367-16386 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 7b
  • western blot; human
Booth L, Roberts J, Poklepovic A, Gordon S, Dent P. PDE5 inhibitors enhance the lethality of pemetrexed through inhibition of multiple chaperone proteins and via the actions of cyclic GMP and nitric oxide. Oncotarget. 2017;8:1449-1468 pubmed publisher
  • immunocytochemistry; human; fig 8
  • western blot; human
Tavallai M, Booth L, Roberts J, Poklepovic A, Dent P. Rationally Repurposing Ruxolitinib (Jakafi (®)) as a Solid Tumor Therapeutic. Front Oncol. 2016;6:142 pubmed publisher
  • western blot; human
Booth L, Albers T, Roberts J, Tavallai M, Poklepovic A, Lebedyeva I, et al. Multi-kinase inhibitors interact with sildenafil and ERBB1/2/4 inhibitors to kill tumor cells in vitro and in vivo. Oncotarget. 2016;7:40398-40417 pubmed publisher
  • western blot; human
Booth L, Roberts J, Tavallai M, Chuckalovcak J, Stringer D, Koromilas A, et al. [Pemetrexed + Sorafenib] lethality is increased by inhibition of ERBB1/2/3-PI3K-NFκB compensatory survival signaling. Oncotarget. 2016;7:23608-32 pubmed publisher
  • immunocytochemistry; human; fig 3d
  • western blot; human
Booth L, Shuch B, Albers T, Roberts J, Tavallai M, Proniuk S, et al. Multi-kinase inhibitors can associate with heat shock proteins through their NH2-termini by which they suppress chaperone function. Oncotarget. 2016;7:12975-96 pubmed publisher
product information
AntibodyID :
30306
AntibodyName :
LS-C31836
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
HSPB1 / HSP27 Antibody (C-Terminus) LS-C31836
Specificity :
Human HSPB1
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
C-Terminus
PresentationDesc :
PBS, 0.09% sodium azide, 2% sucrose
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide from C-Terminus of human HSPB1 (P04792, NP_001531). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey (100%); Marmoset (84%).
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
IsotypeName :
IgG
Gene :
HSPB1 / HSP27
BlockingPeptide :
LS-E10510
StandardGeneSymbol :
HSPB1
Reactivity :
Human, Monkey
Usage :
IHC, IHC-P, WB (1.25 µg/ml)
ShortWebDescription :
HSP27 antibody LS-C31836 is an unconjugated rabbit polyclonal antibody to HSP27 (HSPB1) (C-Terminus) from human. It is reactive with human and monkey. Validated for IHC and WB. Cited in 6 publications.
Synonyms :
HSPB1, 28 kDa heat shock protein, Heat shock 27 kDa protein, Heat shock 27kD protein 1, Heat shock 27kDa protein 1, HSP27, HSP28, HSP 27, Hsp25, SRP27, Stress-responsive protein 27, CMT2F, Heat shock 27 kd protein, Heat shock protein beta-1, HMN2B, HS.76067
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.