product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IL18 Antibody (aa37-193) LS-C313397
catalog :
LS-C313397
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section
citations: 2
Reference
Gritsenko A, Yu S, Martín Sánchez F, Díaz Del Olmo I, Nichols E, Davis D, et al. Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro. Front Immunol. 2020;11:565924 pubmed publisher
Palazón Riquelme P, Worboys J, Green J, Valera A, Martín Sánchez F, Pellegrini C, et al. USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation. EMBO Rep. 2018;19: pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-C313397 image 1
IL18 antibody. IHC(P): Human Tonsil Tissue.
image 2 :
LifeSpan Biosciences LS-C313397 image 2
WB of IL18 antibody. All lanes: Anti-IL18 at 0.5ug/ml. WB: Recombinant Human IL18 Protein 0.5ng. Predicted bind size: 24KD. Observed bind size: 24KD.
product information
AntibodyID :
323369
AntibodyName :
LS-C313397
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IL18 Antibody (aa37-193) LS-C313397
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa37-193
PresentationDesc :
Lyophilized from 0.2mg Na2HPO4, 5mg BSA, 0.9mg NaCl, 0.05mg sodium azide.
ImmunogenDesc :
E.coli-derived human IL-18 recombinant protein (Position: Y37-D193). Human IL-18 shares 66% and 64% amino acid (aa) sequences identity with mouse and rat IL-18, respectively.
PurificationDesc :
Immunogen affinity purified
RecommendedStorageDesc :
At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid freeze-thaw cycles.
ResuspensionLiquidDesc :
Add 0.2ml of distilled water will yield a concentration of 500µg/ml.
IsotypeName :
IgG
Gene :
IL18
StandardGeneSymbol :
IL18
gene family :
IL-1
Reactivity :
Human
Usage :
ELISA, IHC, IHC-P (1 µg/ml), WB (0.5 µg/ml)
ShortWebDescription :
IL18 antibody LS-C313397 is an unconjugated rabbit polyclonal antibody to human IL18 (aa37-193). Validated for ELISA, IHC and WB. Cited in 2 publications.
UsageText :
IHC-P: HIER antigen retrieval with 10 mM sodium citrate buffer pH 6.0, 20 minutes at 99-100C is recommended.
Synonyms :
IL18, IGIF, IL-1g, Interleukin-18, IFN-gamma-inducing factor, IL-1 gamma, IL-18, Iboctadekin, IL1F4, Interleukin-1 gamma
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.