This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CMA1 / Mast Cell Chymase Antibody (Azide-free) LS-C25451
catalog :
LS-C25451
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
26033
AntibodyName :
LS-C25451
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
CMA1 / Mast Cell Chymase Antibody (Azide-free) LS-C25451
Specificity :
May be used to detect mast cells in routinely fixed tissues and has been used to study the distribution of mast cells in skin, synovium, lung and heart. Binding of this antibody to chymase is not reduced in the presence of heparin, suggesting that the antibody does not bind to the heparin-binding domain of chymase. Species cross-reactivity: human.
ClonalityDesc :
Monoclonal
AntibodyModification :
Azide-free Unconjugated
PresentationDesc :
10 mM PBS, pH 7.4
ImmunogenType :
Purified protein
ImmunogenDesc :
Purified human skin chymase.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
CMA1 / Mast Cell Chymase
StandardGeneSymbol :
CMA1
gene family :
Protease
Subfamily :
Serine S1
Reactivity :
Human
Usage :
IHC, IHC-P, WB
ShortWebDescription :
Mast Cell Chymase antibody LS-C25451 is an unconjugated mouse monoclonal antibody to human Mast Cell Chymase (CMA1). Validated for IHC and WB.
UsageText :
Western Blot1 (Ab 1-2 ug/ml for 2hrs at RT). Immunohistochemistry (Formalin/paraffin) (Use Ab at 0.06-0.12 ug/ml for 30 min at RT). Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Positive control: Tonsil. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Synonyms :
CMA1, Chymase, Chymase, heart, Chymase, mast cell, CYH, Mast cell chymase, Mcpt5, MCT1, Mast cell protease 5, Mast cell protease I, Heart chymase, Alpha-chymase, Chymase 1, Chymase 1, mast cell, CYM
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.
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