This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CCND1 / Cyclin D1 Antibody LS-C22522
catalog :
LS-C22522
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry
product information
AntibodyName :
LS-C22522
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
CCND1 / Cyclin D1 Antibody LS-C22522
Specificity :
Cyclin D1 is a 36 kD nuclear protein. The cell cycle in eukaryotic cells is mediated by the formation, activation and deactivation of complexes containing Cyclin-Dependent Kinases (CDK) and cyclins. D-type cyclins usually associate with CDK4 (p34 PSK-J3 ); however, complexes with CDK2 and CDK5 have also been reported. D-type cyclins are necessary for cells to achieve the G1 to S transition in the cell cycle. The D-type cyclins have been shown to associate with PCNA, retinoblastoma gene product, p21 and other proteins.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.2, 0.1% Sodium Azide, 1% BSA
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant full-length human cyclin D1 protein.
PurificationDesc :
Purified
RecommendedStorageDesc :
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
IsotypeName :
IgG2a,k
Gene :
CCND1 / Cyclin D1
StandardGeneSymbol :
CCND1
Reactivity :
Human
Usage :
IHC (1:100)
ShortWebDescription :
Cyclin D1 antibody LS-C22522 is an unconjugated mouse monoclonal antibody to human Cyclin D1 (CCND1). Validated for IHC.
UsageText :
Suitable for use in Immunohistochemistry. Immunohistochemistry: 1:100. Epitope Retrieval with EDTA pH 8.0 is required. Positive control: Mantle cell lymphoma.
Synonyms :
CCND1, B-cell lymphoma 1 protein, BCL-1 oncogene, B-cell CLL/lymphoma 1, BCL-1, Cyclin D1, G1/S-specific cyclin-D1, U21B31, PRAD1, BCL1, D11S287E, PRAD1 oncogene
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.