This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Complement C3 Antibody (clone H13) LS-C22305
catalog :
LS-C22305
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H13

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - frozen section
product information
AntibodyID :
22887
AntibodyName :
LS-C22305
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
Complement C3 Antibody (clone H13) LS-C22305
Specificity :
Recognizes a C3a-determinant (C3 alpha-chain) which is present also on native C3. Allows discrimination of ubiquitous or nonspecifically bound native C3 from biologically active C3b fragment, C3b or C are negative with this clone. The antibody inhibits the anaphylactic function of C3a: the capacity of C3a to induce serotonin release from thrombocytes in vitro is inhibited; similarly, treatment of C3a with the antibody inhibits the C3a-induced skin reaction in vivo. Species cross-reactivity: Guinea pig and rabbit C3/C3a.
ClonalityDesc :
Monoclonal
CloneName :
H13
AntibodyModification :
Unconjugated
PresentationDesc :
Lyophilized from PBS, pH 7.4, 0.5% BSA, 0.9% sodium azide
ImmunogenType :
Purified protein
ImmunogenDesc :
Human complement component C3.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Lyophilized and resuspended forms: store at -20°C.
ResuspensionLiquidDesc :
Reconstitute with 1.0 ml sterile ddH2O
IsotypeName :
IgG2b
Gene :
Complement C3
StandardGeneSymbol :
C3
Reactivity :
Rabbit, Guinea pig, Human
Usage :
IHC, IHC-Fr, WB
ShortWebDescription :
Complement C3 antibody LS-C22305 is an unconjugated mouse monoclonal antibody to Complement C3 from human. It is reactive with human, guinea pig and rabbit. Validated for IHC and WB.
UsageText :
Suitable for use in Immunohistochemistry (frozen sections) and Western blotting. The antibody is, in combination with antibodies to the C3b fragment, an excellent control for distinguishing ubiquitous or nonspecifically bound native C3 from the biologically active C3 fragment. Nonactivated C3 still bears the C3a determinant, whereas activated C3 (C3b, C3d) is C3a-negative. It is therefore useful for immunopathological assays (demonstration of C3 deposition in biopsies) and for C3a assays research purposes.
Synonyms :
C3, AHUS5, ARMD9, Complement component C3, CPAMD1, Complement C3, ASP, Complement component 3
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.