This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
BLNK Antibody (aa171-356, Concentrated) LS-C202774
catalog :
LS-C202774
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
product information
AntibodyID :
211030
AntibodyName :
LS-C202774
TargetSpecies :
Mouse
Host Species :
Rabbit
Product Name :
BLNK Antibody (aa171-356, Concentrated) LS-C202774
Specificity :
BLNK (B cell linker protein) is an adaptor molecule that plays key role in B cell activation initiated by cross-linking the B cell receptor (BCR). This activation leads to an increase in the tyrosine phosphorylation of a number of proteins due to activation of nonreceptor protein tyrosine kinases (PTK) including Syk, which is responsible for the tyrosine phosphorylation of BLNK. BLNK is cytosolic protein identified as two phosphoproteins migrating at 68 and 70 kD in SDS/PAGE (alternatively spliced forms of human BLNK). Mapping of the tyrosine residues in BLNK reveal three tyrosines that bind PLC-gamma2, and two tyrosines that bind the Tec family kinase Btk, the Vav nucleotide exchange factor and the adaptor Nck.
ClonalityDesc :
Polyclonal
AntibodyModification :
Concentrated Unconjugated
AntigenModification :
aa171-356
PresentationDesc :
PBS, pH 7.4, 15 mM Sodium Azide
ImmunogenType :
Fusion protein
ImmunogenDesc :
A fusion protein representing amino acids 171-356 of human BLNK.
PurificationDesc :
Purified
RecommendedStorageDesc :
Store at 2-8°C.
Gene :
BLNK
StandardGeneSymbol :
BLNK
gene family :
Signal Transduction
Reactivity :
Mouse
Usage :
WB
ShortWebDescription :
BLNK antibody LS-C202774 is an unconjugated rabbit polyclonal antibody to mouse BLNK (aa171-356). Validated for WB.
Synonyms :
BLNK, AGM4, BLNK-S, B-cell activation, B-cell linker protein, B cell linker protein, Bca, Cytoplasmic adapter protein, LY57, SLP-65, SLP65, B-cell linker, BASH
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.