This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
EMA / MUC1 Antibody (clone VU-4H5, Concentrated) LS-C202433
catalog :
LS-C202433
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
VU-4H5

The same clone is also sold as:
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
AntibodyID :
210689
AntibodyName :
LS-C202433
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
EMA / MUC1 Antibody (clone VU-4H5, Concentrated) LS-C202433
Specificity :
VU-4H5 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is upregulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. The dominant epitope of mAb VU4H5 is APDTR as established with epitope fingerprinting.
ClonalityDesc :
Monoclonal
CloneName :
VU-4H5
AntibodyModification :
Concentrated Unconjugated
PresentationDesc :
PBS, 0.05% Sodium Azide
ImmunogenDesc :
A MUC1 60mer tandem repeat NH2-(VTSAPDTRPAPGSTAPPAHG)3-COOH conjugated to bovine serum albumin. Splenocytes were fused with SP2/0 mouse myeloma cells. Stability of the hybridomas was established by subcloning four times.
PurificationDesc :
Purified
RecommendedStorageDesc :
Store at 2-8°C. Do not freeze.
IsotypeName :
IgG1
Gene :
EMA / MUC1
StandardGeneSymbol :
MUC1
gene family :
Mucin
Reactivity :
Human
Usage :
ELISA, IHC, IHC-Fr, IHC-P
ShortWebDescription :
MUC1 antibody LS-C202433 is an unconjugated mouse monoclonal antibody to human MUC1 (EMA). Validated for ELISA and IHC.
Synonyms :
MUC1, CA15-3, CD227, Carcinoma-associated mucin, CD227 antigen, DF3 antigen, Episialin, Epithelial membrane antigen, H23 antigen, H23AG, Krebs von den Lungen-6, MAM6, MUC1/ZD, MUC-1/SEC, Mucin-1, Pem, KL-6, MUC-1/X, Tumor-associated mucin, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, PUM, EMA, MUC-1, Mucin 1, transmembrane
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.