This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CD1D Antibody (clone WTH1, Biotin) LS-C188719
catalog :
LS-C188719
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
WTH1

The same clone is also sold as:
reactivity :
human, rat
application :
western blot, ELISA, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
196622
AntibodyName :
LS-C188719
TargetSpecies :
Rat
Host Species :
Mouse
Product Name :
CD1D Antibody (clone WTH1, Biotin) LS-C188719
Specificity :
Recognizes rat CD1d, a glycoprotein expressed on cortical thymocytes, certain T-cell leukemias and various other antigen presenting cells. CD1d binds self and non-self glycolipids and presents them to T-cell receptors on natural killer cells. When activated, natural killer cells produce Th1 and Th2 cytokines. Clone WTH1 recognizes a different, non-overlapping epitope than clone WTH2 (, or ), and binds with high affinity to the mature CD1d heavy chain independently of beta-2-microglobulin. Clone WTH1 efficiently blocks rat and mouse invariant natural killer T cell (iNKT cell) response to a-GalCer (an antigen for iNKT cells) and has a slightly higher affinity to native CD1d than clone WTH2. Clone WTH1 cross reacts weakly with mouse tissue in IHC and western blotting, but reacts strongly with both rat and mouse antigens in flow cytometry and immunoprecipitation.
ClonalityDesc :
Monoclonal
CloneName :
WTH1
AntibodyModification :
Biotin
PresentationDesc :
PBS, 0.02% Sodium Azide
ImmunogenType :
Cells
ImmunogenDesc :
Rat CD1d-transduced M12.4.1. C3 cells.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG2a
Gene :
CD1D
StandardGeneSymbol :
CD1D
Reactivity :
Rat
Usage :
ELISA, Flo (1:1000), IHC-Fr, IP, WB
ShortWebDescription :
CD1D antibody LS-C188719 is a biotin-conjugated mouse monoclonal antibody to rat CD1D. Validated for ELISA, Flow, IHC, IP and WB.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Synonyms :
CD1D, CD1D antigen, d polypeptide, R3, R3G1, CD1d antigen, CD1d molecule, Thymocyte antigen CD1D
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.