This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
TREM2 / TREM-2 Antibody (clone 78.18, Low Endotoxin) LS-C188610
catalog :
LS-C188610
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
78.18

The same clone is also sold as:
reactivity :
human, mouse
application :
flow cytometry
product information
AntibodyID :
196513
AntibodyName :
LS-C188610
TargetSpecies :
Mouse
Host Species :
Rat
Product Name :
TREM2 / TREM-2 Antibody (clone 78.18, Low Endotoxin) LS-C188610
Specificity :
Recognizes Triggering receptor expressed on myeloid cells 2 (TREM-2), an activating receptor of the Ig superfamily. TREM-2 forms a receptor signalling complex with DAP12 to trigger the activation of the immune response in macrophages and dendritic cells. It may be involved in chronic inflammation and may promote the production of constitutive rather than inflammatory chemokines and cytokines. TREM-2 may also have a functional role in osteoclast formation. Stimulation of TREM-2 with clone 78.18 enhances multinucleated osteoclast formation in vitro. Clone 78.18 may also be used to block TREM-2 on pre-osteoclasts to inhibit the formation of multinuclear osteoclasts and to inhibit bone resorption by mature osteoclasts.
ClonalityDesc :
Monoclonal
CloneName :
78.18
AntibodyModification :
Low Endotoxin Unconjugated
PresentationDesc :
PBS
ImmunogenType :
Fusion protein
ImmunogenDesc :
Mouse TREM-2 Fc fusion protein.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
TREM2 / TREM-2
StandardGeneSymbol :
TREM2
Reactivity :
Mouse
Usage :
Flo (1:25 - 1:200)
ShortWebDescription :
TREM-2 antibody LS-C188610 is an unconjugated rat monoclonal antibody to mouse TREM-2 (TREM2). Validated for Flow.
UsageText :
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Synonyms :
TREM2, Trem2b, TREM-2, Trem2a, Trem2c
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.