This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
TUBB3 / Tubulin Beta 3 Antibody (clone AA10) LS-C188587
catalog :
LS-C188587
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AA10
reactivity :
human, rat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
AntibodyID :
196490
AntibodyName :
LS-C188587
TargetSpecies :
Rat
Host Species :
Mouse
Product Name :
TUBB3 / Tubulin Beta 3 Antibody (clone AA10) LS-C188587
Specificity :
Recognizes tubulin beta 3. Dimers of alpha and beta tubulin bind to two GTP molecules and assemble into microtubules. The GTP bound to the beta tubulin subunit eventually hydrolyses into GDP. This GTP cycle is essential for microtubule stability, as dimers bound to GTP tend to assemble into microtubules, whereas dimers bound to GDP tend to be unstable. The tubulin beta 3 chain (also known as neuron-specific class III beta-tubulin) are found exclusively in neurons and serves as a neuronal marker. It has also been found in cancer cells and correlates with an increasing histological degree of malignancy.
ClonalityDesc :
Monoclonal
CloneName :
AA10
AntibodyModification :
Unconjugated
PresentationDesc :
10 mM HEPES, pH 7.5, 150 mM NaCl, 0.09% Sodium Azide, 50% Glycerol, 0.01% BSA
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to Tubulin Beta 3.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG
Gene :
TUBB3 / Tubulin Beta 3
StandardGeneSymbol :
TUBB3
gene family :
Tubulin
Reactivity :
Rat
Usage :
IHC, IHC-Fr (1:1000), IHC-P (1:1000), WB (1:10000)
ShortWebDescription :
Tubulin Beta 3 antibody LS-C188587 is an unconjugated mouse monoclonal antibody to rat Tubulin Beta 3 (TUBB3 ). Validated for IHC and WB.
Synonyms :
TUBB3, CDCBM, Beta III Tubulin, Class III beta-tubulin, TUBB4, Tubulin, beta 3, Tubulin beta-III, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin, beta 3 class III, CFEOM3A
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.