Rhodopsin / RHO Antibody (clone 1D4) LS-C188582 | LifeSpan Biosciences LS-C188582 product information

product summary

company name :

LifeSpan Biosciences

product type :

antibody

product name :

Rhodopsin / RHO Antibody (clone 1D4) LS-C188582

catalog :

LS-C188582

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1D4

reactivity :

human, rat, bovine

application :

western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

LifeSpan Biosciences product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; rat; 1:200; loading ...; fig 6a	Greferath U, Huynh M, Jobling A, Vessey K, Venables G, Surrao D, et al. Dorsal-Ventral Differences in Retinal Structure in the Pigmented Royal College of Surgeons Model of Retinal Degeneration. Front Cell Neurosci. 2020;14:553708 pubmed publisher

product information

AntibodyID :

196485

AntibodyName :

LS-C188582

TargetSpecies :

Bovine

Host Species :

Mouse

Product Name :

Rhodopsin / RHO Antibody (clone 1D4) LS-C188582

Specificity :

Recognizes rhodopsin, a pigment of the retina responsible for the formation of photoreceptor cells and the first events in the perception of light. Rhodopsin consists of the protein opsin and a reversibly bound cofactor, retinal, a photoreactive chromophore. Upon light absorption the 11-cis-retinal is isomerized to all-trans retinal, leading to a change in the shape of rhodopsin. The change activates the associated G protein and triggers a second messenger cascade, eventually resulting in the transmission of a nerve impulse to the brain. The trans-retinal is released and converted back into 11-cis-retinal for re-entry into the cycle. Defects in the gene cause various retinopathies such as retinitis pigmentosa and X-linked congenital stationary night blindness.

ClonalityDesc :

Monoclonal

CloneName :

1D4

AntibodyModification :

Unconjugated

PresentationDesc :

10mM HEPES, pH 7.5, 150mM NaCl, 0.09% Sodium Azide, 50% Glycerol, 0.01% BSA

ImmunogenType :

Purified protein

ImmunogenDesc :

Bovine rhodopsin.

PurificationDesc :

Protein G purified

RecommendedStorageDesc :

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

IsotypeName :

IgG1

Gene :

Rhodopsin / RHO

StandardGeneSymbol :

RHO

gene family :

GPCR

Subfamily :

Opsin

Reactivity :

Bovine

Usage :

IF, IHC-P (1:100), IP, WB (1:1000)

ShortWebDescription :

RHO antibody LS-C188582 is an unconjugated mouse monoclonal antibody to bovine RHO (Rhodopsin). Validated for IF, IHC, IP and WB.

Synonyms :

RHO, CSNBAD1, OPN2, Rhodopsin, RP4, Opsin 2, rod pigment, Opsin-2

SalesRegion :

Worldwide

more info or order :

LifeSpan Biosciences product webpage

company information

LifeSpan Biosciences

2401 Fourth Avenue, Suite 900
Seattle, WA 98121

CustomerSupport@lsbio.com

https://www.lsbio.com

1-206-464-1554

headquarters: USA

Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.