This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
GFAP Antibody (clone 1B4) LS-C188569
catalog :
LS-C188569
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1B4

The same clone is also sold as:
reactivity :
human, bovine
application :
western blot, radioimmunoassay, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
AntibodyID :
196472
AntibodyName :
LS-C188569
TargetSpecies :
Bovine
Host Species :
Mouse
Product Name :
GFAP Antibody (clone 1B4) LS-C188569
Specificity :
Recognizes glial fibrillary acidic protein, or GFAP, a class III intermediate filament. During development of the central nervous system, GFAP distinguishes astrocytes from other glial cells. It is involved in various cellular functions, such as cell structure and movement, cell communication and the functioning of the blood-brain barrier. It also plays a role in mitosis by adjusting the filament network present in the cell. Defects in GFAP are a cause of Alexander disease, a rare disorder of the central nervous system affecting mostly males. It is a progressive leukoencephalopathy resulting in mental and physical retardation, dementia, seizures and early death. The antibody may be used in conjunction with clones 4A11 and 2E1 for increased sensitivity when used in immunohistology.
ClonalityDesc :
Monoclonal
CloneName :
1B4
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Tissue extract
ImmunogenDesc :
Bovine spinal cord homogenate
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG2b
Gene :
GFAP
StandardGeneSymbol :
GFAP
Reactivity :
Bovine
Usage :
IHC-Fr, IHC-P (1:200 - 1:1000), RIA, WB
ShortWebDescription :
GFAP antibody LS-C188569 is an unconjugated mouse monoclonal antibody to bovine GFAP. Validated for IHC, RIA and WB.
Synonyms :
GFAP
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.