This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CD105 Antibody (clone MJ7/18) LS-C188547
catalog :
LS-C188547
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MJ7/18

The same clone is also sold as:
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
AntibodyID :
196450
AntibodyName :
LS-C188547
TargetSpecies :
Mouse
Host Species :
Rat
Product Name :
CD105 Antibody (clone MJ7/18) LS-C188547
Specificity :
Recognizes mouse CD105, also known as Endoglin, a cell surface glycoprotein member of the TGF beta receptor complex. CD105 is a homodimer that forms a heteromeric complex with TGF beta receptors I and/or II. The complex binds TGF beta 1 and 3 efficiently, and TGF beta 2 less efficiently. It may also play a role in the binding of endothelial cells to integrins and cytoskeletal organisation. It is involved in cardiovascular development. CD105 is expressed on endothelial cells in all tissues except bone marrow and in also found in stromal cells within the connective tissue of the intestine, stomach and heart. It may be a useful marker for proliferating endothelium in tumors.
ClonalityDesc :
Monoclonal
CloneName :
MJ7/18
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Tissue
ImmunogenDesc :
Inflamed mouse skin.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG2a
Gene :
CD105
StandardGeneSymbol :
ENG
Reactivity :
Mouse
Usage :
Flo (1:10 - 1:20), IHC, IHC-Fr, IHC-P, IP, WB
ShortWebDescription :
CD105 antibody LS-C188547 is an unconjugated rat monoclonal antibody to mouse CD105. Validated for Flow, IHC, IP and WB.
Synonyms :
ENG, CD105, CD105 antigen, END, HHT1, ORW, ORW1, Osler-Rendu-Weber syndrome 1, Endoglin
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.