This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
ITGAE / CD103 Antibody (clone 2E7) LS-C188546
catalog :
LS-C188546
clonality :
monoclonal
host :
hamsters
conjugate :
nonconjugated
clone name :
2E7

The same clone is also sold as:
reactivity :
human, mouse
application :
immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
196449
AntibodyName :
LS-C188546
TargetSpecies :
Mouse
Host Species :
Hamster
Product Name :
ITGAE / CD103 Antibody (clone 2E7) LS-C188546
Specificity :
Recognizes mouse CD103, otherwise known as Integrin alpha-E. CD103 binds Integrin beta 7 to form the heterodimeric integrin molecule aE7. This complex is sometimes referred to as CD103, though strictly speaking CD103 only refers to the alpha chain. The beta 7 subunit can also interact with other integrin alpha chains. The aE7 complex is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. CD103 is expressed on intestinal intraepithelial lymphocytes and is highly expressed on regulatory T cells. Clone 2E7 has been reported to also recognize the aE7 complex.
ClonalityDesc :
Monoclonal
CloneName :
2E7
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenDesc :
Mouse intestinal intraepithelial lymphocytes.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG
Gene :
ITGAE / CD103
StandardGeneSymbol :
ITGAE
gene family :
Integrin
Reactivity :
Mouse
Usage :
Flo (1:10 - 1:20), IF, IHC-Fr, IP
ShortWebDescription :
CD103 antibody LS-C188546 is an unconjugated hamster monoclonal antibody to mouse CD103 (ITGAE). Validated for Flow, IF, IHC and IP.
UsageText :
Tested in IF only with frozen sections fixed in acetone.
Synonyms :
ITGAE, CD103, CD103 antigen, Integrin alpha-E, HML-1 antigen, Integrin alpha-IEL, Alpha polypeptide), Mucosal lymphocyte 1 antigen, HUMINAE
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.