This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
TNFSF4 / OX40L / CD252 Antibody (clone ATM-2, RPE) LS-C188469
catalog :
LS-C188469
clonality :
monoclonal
host :
mouse
conjugate :
RPE
clone name :
ATM-2

The same clone is also sold as:
reactivity :
human, rat
application :
flow cytometry
product information
AntibodyID :
196372
AntibodyName :
LS-C188469
TargetSpecies :
Rat
Host Species :
Mouse
Product Name :
TNFSF4 / OX40L / CD252 Antibody (clone ATM-2, RPE) LS-C188469
Specificity :
Recognizes rat CD252, otherwise known as OX40L or CD134L, a 22kD type II transmembrane glycoprotein and member of the TNF superfamily, expressed by antigen-presenting cells including activated dendritic cells and B cells, and also by vascular endothelium. The interaction of CD252 with its receptor OX40/CD134, acts as a co-stimulator of T cell activation, proliferation and both Th1 and Th2 cytokine production, and is also important in activated B cell proliferation and secretion of immunoglobulins (Igs). CD252/OX40 interaction has been implicated in HTLV-1 associated diseases including myelopathy and adult T cell leukaemia, and also with the autoimmune diseases rheumatoid arthritis and inflammatory bowel disease. Clone ATM-2 has been shown to block the co-stimulatory activity of CD252 on rat T cell proliferation.
ClonalityDesc :
Monoclonal
CloneName :
ATM-2
AntibodyModification :
RPE
PresentationDesc :
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
ImmunogenType :
Cells
ImmunogenDesc :
ACI-S1 rat T-cell lymphoma cell line.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
ResuspensionLiquidDesc :
Reconstitute with distilled water.
IsotypeName :
IgG1
Gene :
TNFSF4 / OX40L / CD252
StandardGeneSymbol :
TNFSF4
gene family :
TNF
Reactivity :
Rat
Usage :
Flo (1:1)
ShortWebDescription :
CD252 antibody LS-C188469 is an RPE-conjugated mouse monoclonal antibody to rat CD252 (TNFSF4 / OX40L). Validated for Flow.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Synonyms :
TNFSF4, CD134 ligand, CD134L, CD252 antigen, Glycoprotein Gp34, OX-40L, OX40 ligand, TXGP1, OX40L, OX4OL, CD252, gp34, OX40 antigen ligand
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.