This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
VCAM1 / CD106 Antibody (clone MR106) LS-C188465
catalog :
LS-C188465
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MR106
reactivity :
human, rat
application :
immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
196368
AntibodyName :
LS-C188465
TargetSpecies :
Rat
Host Species :
Mouse
Product Name :
VCAM1 / CD106 Antibody (clone MR106) LS-C188465
Specificity :
Recognizes rat CD106, otherwise known as VCAM-1 (vascular adhesion molecule 1), a 110kD inducible type I transmembrane glycoprotein and member of the immunoglobulin supergene family, which is predominantly expressed on vascular endothelium, and also on bone marrow stromal cells, follicular dendritic cells and some macrophages. CD106 interacts with the lymphocyte homing receptor VLA-4 (alpha4 beta1 integrin) and LPAM-1 (alpha4 beta7 integrin) and mediates leucocyte-endothelial cell adhesion and signal transduction. Expression of CD106 is upregulated following cytokine activation, and endothelial CD106 plays a role in the extravasation of leucocytes from blood vessels during inflammation.
ClonalityDesc :
Monoclonal
CloneName :
MR106
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenDesc :
Rat CD106-transfected L5178Y cells.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
VCAM1 / CD106
StandardGeneSymbol :
VCAM1
gene family :
ICAM
Reactivity :
Rat
Usage :
Flo (1:1 - 1:25), IF, IHC-Fr
ShortWebDescription :
CD106 antibody LS-C188465 is an unconjugated mouse monoclonal antibody to rat CD106 (VCAM1 ). Validated for Flow, IF and IHC.
Synonyms :
VCAM1, CD106, CD106 antigen, INCAM-100, V-CAM 1, VCAM-1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.