This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
HRAS / H-Ras Antibody (clone H-Ras-03) LS-C188430
catalog :
LS-C188430
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H-Ras-03

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA
product information
AntibodyID :
196333
AntibodyName :
LS-C188430
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
HRAS / H-Ras Antibody (clone H-Ras-03) LS-C188430
Specificity :
Recognizes human H-Ras, otherwise known as p21Ras, a ubiquitously expressed lipid-anchored GTPase and member of the Ras superfamily of small GTPases, which acts as a molecular signal transduction on/off switch on the inner surface of the plasma membrane and endomembranes. H-Ras, N-Ras and K-Ras4A/4B are highly related RAS genes which regulate pathways involved in cell differentiation, proliferation, adhesion, migration and apoptosis and are known proto-oncogenes. Mutations in the H-Ras gene are responsible for the rare condition known as Costello syndrome characterized by facial, cardiovascular and musculoskeletal abnormalities and mental retardation.
ClonalityDesc :
Monoclonal
CloneName :
H-Ras-03
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to amino acids DIHQYREQIKRVKDSDDC of human H-Ras. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Monkey, Galago, Marmoset, Mouse, Rat, Shrew, Hamster, Panda, Bovine, Dog, Cat, Horse, Pig, Opossum, Guinea pig, Zebra finch, Chicken, Lizard, Xenopus, Catfish, Salmon, Stickleback, Medaka, Pufferfish, Zebrafish (100%); Turkey, Trout (88%).
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
HRAS / H-Ras
StandardGeneSymbol :
HRAS
gene family :
Ras GTPase superfamily IPR001806
Subfamily :
RAS oncogene
Reactivity :
Human
Usage :
ELISA, WB (0.5 - 1 µg/ml)
ShortWebDescription :
H-Ras antibody LS-C188430 is an unconjugated mouse monoclonal antibody to human H-Ras (HRAS). Validated for ELISA and WB.
Synonyms :
HRAS, C-H-RAS, C-has/bas p21 protein, C-ras-Ki-2 activated oncogene, C-HA-RAS1, CTLO, H-ras, H-RASIDX, GTP- and GDP-binding peptide B, GTPase HRas, H-Ras-1, HAMSV, HRAS1, K-RAS, Ha-Ras, Ha-Ras1 proto-oncoprotein, Transforming protein p21, N-ras, p21ras, RASH1, C-BAS/HAS, C-ha-ras, p19 H-RasIDX protein
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.