This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CD86 Antibody (clone 24F, RPE) LS-C188425
catalog :
LS-C188425
clonality :
monoclonal
host :
mouse
conjugate :
RPE
clone name :
24F

The same clone is also sold as:
reactivity :
human, rat
application :
flow cytometry
product information
AntibodyID :
196328
AntibodyName :
LS-C188425
TargetSpecies :
Rat
Host Species :
Mouse
Product Name :
CD86 Antibody (clone 24F, RPE) LS-C188425
Specificity :
Recognizes rat CD86, otherwise known as B7-2, a type I transmembrane protein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells, and also on germinal centre B cells and macrophages. Like CD80, CD86 is an accessory molecule which functions in the CD28-CD80/CD86 co-stimulatory pathway, vital for T cell activation, crosstalk between T and B cells, and Th2-mediated Ig production. Clone 24F has been shown to block the co-stimulatory activity of rat CD86.
ClonalityDesc :
Monoclonal
CloneName :
24F
AntibodyModification :
RPE
PresentationDesc :
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
ImmunogenType :
Cells
ImmunogenDesc :
HTLV-1 transformed Lewis - S1 cells.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
ResuspensionLiquidDesc :
Reconstitute with distilled water.
IsotypeName :
IgG1
Gene :
CD86
StandardGeneSymbol :
CD86
Reactivity :
Rat
Usage :
Flo (1:1)
ShortWebDescription :
CD86 antibody LS-C188425 is an RPE-conjugated mouse monoclonal antibody to rat CD86. Validated for Flow.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Synonyms :
CD86, Activation B7-2 antigen, B7-2, B7.2, B70, CD86 molecule, CTLA-4 counter-receptor B7.2, CD86 antigen, FUN-1, LAB72, BU63, CD28LG2, Ctla-4 counter-receptors b7.2
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.