This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CD14 Antibody (clone biG57, RPE) LS-C188394
catalog :
LS-C188394
clonality :
monoclonal
host :
mouse
conjugate :
RPE
clone name :
biG57
reactivity :
human, mouse
application :
flow cytometry
product information
AntibodyID :
196297
AntibodyName :
LS-C188394
TargetSpecies :
Mouse
Host Species :
Mouse
Product Name :
CD14 Antibody (clone biG57, RPE) LS-C188394
Specificity :
Recognizes mouse CD14, a 55kD a glycophosphoinositol-linked cell surface protein that also exists in a soluble form. Expression of CD14 is restricted to the myeloid lineage and is predominantly expressed on peripheral blood monocytes, weakly expressed on granulocytes and absent on myeloid progenitors. The CD14 molecule acts as a pattern recognition receptor, which binds lipopolysaccharide (LPS) and other microbial products such as lipoteichoic acid, lipoproteins and peptidoglycan. Binding of LPS to CD14 mediates the innate immune response to LPS and requires the Toll-like receptor-4 (TLR4)/MD-2 complex for effective signalling. Antibodies produced by biG 57 do not inhibit the binding of CD14.
ClonalityDesc :
Monoclonal
CloneName :
biG57
AntibodyModification :
RPE
PresentationDesc :
PBS, 0.09% Sodium Azide, 1% BSA
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant mouse CD14.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C. Do not freeze. Store undiluted. Microcentrifugation recommended if solution contains precipitate.
ResuspensionLiquidDesc :
Reconstitute with distilled water.
IsotypeName :
IgG1
Gene :
CD14
StandardGeneSymbol :
CD14
Reactivity :
Mouse
Usage :
Flo (1:1)
ShortWebDescription :
CD14 antibody LS-C188394 is an RPE-conjugated mouse monoclonal antibody to mouse CD14. Validated for Flow.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Synonyms :
CD14, CD14 molecule, CD14 antigen
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.