This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
LAMP2 / CD107b Antibody (clone AC17) LS-C188336
catalog :
LS-C188336
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AC17
reactivity :
human, dogs
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
product information
AntibodyID :
196239
AntibodyName :
LS-C188336
TargetSpecies :
Dog
Host Species :
Mouse
Product Name :
LAMP2 / CD107b Antibody (clone AC17) LS-C188336
Specificity :
Recognizes canine CD107b, otherwise known as LAMP-2, a 95kD heavily-glycosylated type I integral lysosomal glycoprotein, shown to share high N-terminal amino acid sequence homology with human, mouse and rat CD107b. Lysosomes are membrane-bound organelles found within the cytoplasm of most cells, which contain hydrolytic enzymes and act as the major compartment for heterophagic and autophagic digestion. Members of the lysosomal-associated membrane protein family (LAMPS) are believed to play an important role in protecting the lysosomal membrane from protease degradation and are involved in lectin-mediated cell adhesion. Evidence shows that CD107b is involved in the lysosomal uptake of cytosolic proteins and the endocytic pathway and human studies have revealed a correlation between the level of surface expression of CD107b on tumor cells and their metastatic potential. Clone AC17 has been shown as suitable for use in Electron Microscopy.
ClonalityDesc :
Monoclonal
CloneName :
AC17
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Cells
ImmunogenDesc :
MDCK (Madin-Darby Canine Kidney) cells.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
LAMP2 / CD107b
StandardGeneSymbol :
LAMP2
gene family :
Cancer
Reactivity :
Dog
NonReactiveSpecies :
Mouse, Rat
Usage :
Flo, IF, IP, WB (1:100 - 1:500)
ShortWebDescription :
CD107b antibody LS-C188336 is an unconjugated mouse monoclonal antibody to dog CD107b (LAMP2 ). Validated for Flow, IF, IP and WB.
Synonyms :
LAMP2, CD107b, CD107b antigen, LAMPB, LGP110, LAMP-2
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.