This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CD47 Antibody (clone 1/1A4) LS-C188327
catalog :
LS-C188327
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1/1A4
The same clone is also sold as:
The same clone is also sold as:
- Bio-Rad: MCA2514EL, MCA2514GA, MCA2514A647T, MCA2514, MCA2514A647, MCA2514A488T, MCA2514A488
- MyBioSource: MBS217274
reactivity :
human
application :
immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
196230
AntibodyName :
LS-C188327
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
CD47 Antibody (clone 1/1A4) LS-C188327
Specificity :
Specific for human CD47, also known as integrin-associated protein, a 50kD glycoprotein expressed on all hematopoietic cell lines, epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 is involved in several cellular processes including regulation of T cell and dendritic cell activation, regulation of neutrophil (PMN) chemotaxis, caspase-independent apoptosis, and may act as a signal transducer in the regulation of cation fluxes across cell membranes. CD47 has been identified as a ligand for the inhibitory macrophage receptor known as signal regulatory protein alpha (SIRPalpha) and as a receptor for thrombospondin-1. Cross-linking of CD47 with clone 1/1A4 co-stimulates the proliferation of T cells.
ClonalityDesc :
Monoclonal
CloneName :
1/1A4
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Native protein
ImmunogenDesc :
Human erythrocytes.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG2b
Gene :
CD47
StandardGeneSymbol :
CD47
Reactivity :
Human
Usage :
Flo (1:25 - 1:100), IHC, IHC-Fr, IP
ShortWebDescription :
CD47 antibody LS-C188327 is an unconjugated mouse monoclonal antibody to human CD47. Validated for Flow, IHC and IP.
Synonyms :
CD47, CD47 antigen, CD47 molecule, Integrin associated protein, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6, Rh-related antigen, OA3, CD47 glycoprotein, IAP
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.
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