This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CD209 / DC-SIGN Antibody (clone MR-1, FITC) LS-C188284
catalog :
LS-C188284
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
MR-1

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
product information
AntibodyID :
196187
AntibodyName :
LS-C188284
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
CD209 / DC-SIGN Antibody (clone MR-1, FITC) LS-C188284
Specificity :
Recognizes human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45kD C-type lectin that binds ICAM-3 which is also known as CD209. CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DC's in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DC's and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DC's. Clone MR-1 is reported to partially block the functional activity of DC-SIGN.
ClonalityDesc :
Monoclonal
CloneName :
MR-1
AntibodyModification :
FITC
PresentationDesc :
PBS, 0.09% Sodium Azide, 1% BSA
ImmunogenType :
Cells
ImmunogenDesc :
Immature myeloid monocyte-derived dendritic cells (MDDCs)
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
CD209 / DC-SIGN
StandardGeneSymbol :
CD209
Reactivity :
Human
Usage :
Flo (1:1 - 1:5)
ShortWebDescription :
DC-SIGN antibody LS-C188284 is an FITC-conjugated mouse monoclonal antibody to human DC-SIGN (CD209). Validated for Flow.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Synonyms :
CD209, CD209 antigen, CD209 molecule, CDSIGN, CLEC4L, DC-SIGN, HIV gpl20-binding protein, DC-SIGN1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.