This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
ITGAM / CD11b Antibody (clone CA16.3E10, Supernatant) LS-C188175
catalog :
LS-C188175
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CA16.3E10

The same clone is also sold as:
reactivity :
human, dogs
application :
immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
196078
AntibodyName :
LS-C188175
TargetSpecies :
Dog
Host Species :
Mouse
Product Name :
ITGAM / CD11b Antibody (clone CA16.3E10, Supernatant) LS-C188175
Specificity :
Is a monoclonal antibody recognizing the canine CD11b cell surface antigen, a member of the alpha integrin family. CD11b forms one of the possible alpha chains of the canine leukocyte adhesion complexes (LeuCAMs), these contain a common 95 kD beta chain non-covalently bound to either a 150 kD, 165 kD (CD11b) or 180 kD (CD11a) alpha chain. The CD11/CD18 complex is also known as the CR3 receptor. Canine CD11b is expressed by granulocytes, monocytes, NK cells and some macrophages. Has been used to evaluate the effect of anesthetic administration of CD11b expression on canine neutrophils demonstrating attenuation of CD11b expression at high concentrations administered lidocaine hydrochloride and reduced adhesion of neutrophils to endothelium.
ClonalityDesc :
Monoclonal
CloneName :
CA16.3E10
AntibodyModification :
Supernatant Unconjugated
PresentationDesc :
PBS, 0.1% Sodium Azide
ImmunogenType :
Purified protein
ImmunogenDesc :
Affinity purified beta-2 integrins from splenic lysate.
PurificationDesc :
Tissue culture supernatant
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
ITGAM / CD11b
StandardGeneSymbol :
ITGAM
gene family :
Integrin
Reactivity :
Dog
Usage :
Flo (1:1), IHC-Fr, IP
UsageNotRecommended :
IHC-P
ShortWebDescription :
CD11b antibody LS-C188175 is an unconjugated mouse monoclonal antibody to dog CD11b (ITGAM). Validated for Flow, IHC and IP.
Synonyms :
ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.