product summary
Loading...
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CD8 Antibody (clone YCATE55.9, RPE) LS-C188088
catalog :
LS-C188088
clonality :
monoclonal
host :
rat
conjugate :
RPE
clone name :
YCATE55.9
reactivity :
dogs
application :
flow cytometry
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • flow cytometry; dogs
Maekawa N, Konnai S, Takagi S, Kagawa Y, Okagawa T, Nishimori A, et al. A canine chimeric monoclonal antibody targeting PD-L1 and its clinical efficacy in canine oral malignant melanoma or undifferentiated sarcoma. Sci Rep. 2017;7:8951 pubmed publisher
product information
AntibodyID :
195991
AntibodyName :
LS-C188088
TargetSpecies :
Dog
Host Species :
Rat
Product Name :
CD8 Antibody (clone YCATE55.9, RPE) LS-C188088
Specificity :
Was clustered as Canine CD8 in the First Canine Leukocyte Antigen Workshop. YCATE55.9 reacts with a rat cell line transfected with cDNA for canine CD8alpha and blocks MHC class I dependant T-cell responses in vitro and in vivo. Has been shown to deplete circulating CD8+ T cells when administered to dogs in vivo. Reduced levels of circulating CD8+ T cells has been associated with decreased survival times for dogs with osteosarcoma.
ClonalityDesc :
Monoclonal
CloneName :
YCATE55.9
AntibodyModification :
RPE
PresentationDesc :
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
ImmunogenType :
Fusion protein
ImmunogenDesc :
Canine CD8 alpha chimeric human IgG1 Fc fusion protein.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
ResuspensionLiquidDesc :
Reconstitute with distilled water.
IsotypeName :
IgG1
Gene :
CD8
Reactivity :
Dog
Usage :
Flo (1:1)
ShortWebDescription :
CD8 antibody LS-C188088 is an RPE-conjugated rat monoclonal antibody to dog CD8. Validated for Flow. Cited in 1 publication.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.