This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
PIK3C3 / VPS34 Antibody (aa22-34) LS-C188042
catalog :
LS-C188042
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunocytochemistry
product information
AntibodyID :
195945
AntibodyName :
LS-C188042
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
PIK3C3 / VPS34 Antibody (aa22-34) LS-C188042
Specificity :
Recognizes Phosphatidylinositol 3-kinase catalytic subunit type 3, also known as VPS34 (vacuolar protein sorting 34), PI3-kinase type 3 or PIK3C3. VPS34 is a ubiquitously expressed class III PI3K (phosphoinositide 3-kinase), and member of the PI3/PI4-kinase family, which utilizes phosphatidylinositol (PtdIn) as a substrate, and functions as the catalytic subunit of the PI3K complex. VPS34 plays a role in the transport of lysosomal enzyme precursors to lysosomes, and in endocytosis and vesicular trafficking, and has been strongly implicated as a regulator of autophagy, forming a multi-protein complex with the proautophagic tumor suppressors Beclin1/Atg6, Bif-1, and UVRAG, in the initiation of autophagosome formation. Distinct complexes of VPS34 regulates endocytic processes vital for late-stage autophagosome-lysosome fusion.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa22-34
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
KLH conjugated synthetic peptide corresponding to amino acids 22-34 of human VPS34, The corresponding sequence is identical in mouse and rat.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG
Gene :
PIK3C3 / VPS34
StandardGeneSymbol :
PIK3C3
gene family :
Non-Protein Kinase
Reactivity :
Human
Usage :
IF (1:100), WB (2 - 4 µg/ml)
ShortWebDescription :
VPS34 antibody LS-C188042 is an unconjugated rabbit polyclonal antibody to human VPS34 (PIK3C3) (aa22-34). Validated for IF and WB.
Synonyms :
PIK3C3, HVps34, Phosphatidylinositol 3-kinase, VPS34, PI3-kinase type 3, PI3K type 3, PtdIns-3-kinase type 3
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.