This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CCR5 Antibody (aa3-30) LS-C187838
catalog :
LS-C187838
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
AntibodyID :
195741
AntibodyName :
LS-C187838
TargetSpecies :
Human
Host Species :
Goat
Product Name :
CCR5 Antibody (aa3-30) LS-C187838
Specificity :
Recognizes human CD195, also known as C-C chemokine receptor type 5, CCR5 or C-C CKR-5. CD195 is a 353 amino acid ~37 kD multiple pass transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, preferentially expressed by a subset of memory Th1 (type 1 helper T) cells. Binds to an epitope within the N-terminal (NT) region of CD195. CD195 acts as a high-affinity receptor for several chemotactic chemokines, including MIP-1 alpha (macrophage inflammatory protein 1 alpha), MIP-1 beta, and RANTES (regulated on activation normal T expressed and secreted protein). CD195 is also a major co-receptor for HIV-1 infection, with variations in the CD195 gene, influencing the rate of progression into AIDS. Is suitable for use in immunocytochemistry on human peripheral blood leucocytes.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa3-30
PresentationDesc :
PBS, 0.1% Sodium Azide, 0.1% BSA
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide YQVSSPIYDINYYTSEPCQKINVKQIAA corresponding to amino acids 3-30 within the N-Terminus of human CD195. Percent identity by BLAST analysis: Human (100%); Chimpanzee, Monkey (96%); Orangutan, Baboon (93%).
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG
Gene :
CCR5
StandardGeneSymbol :
CCR5
gene family :
GPCR
Subfamily :
Chemokine
Reactivity :
Human
Usage :
ELISA (1:50000), IHC-Fr, IHC-P (1:300), WB (1:1000)
ShortWebDescription :
CCR5 antibody LS-C187838 is an unconjugated goat polyclonal antibody to human CCR5 (aa3-30). Validated for ELISA, IHC and WB.
Synonyms :
CCR5, C-C chemokine receptor 5, CD195 antigen, CD195, C-C CKR-5, Chemokine c-c motif receptor 5, Chemr13, CMKBR5, CKR5, Cc chemokine receptor 5, CCCKR5, CCR-5, Ccr5 receptor, Chemokine receptor CCR5, HIV-1 fusion coreceptor, IDDM22, C-C chemokine receptor type 5, CC-CKR-5, CKR-5
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.