This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
TLR9 Antibody (aa204-224) LS-C187710
catalog :
LS-C187710
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry - paraffin section
product information
AntibodyID :
195613
AntibodyName :
LS-C187710
TargetSpecies :
Mouse
Host Species :
Goat
Product Name :
TLR9 Antibody (aa204-224) LS-C187710
Specificity :
Recognizes murine Toll-like receptor 9, also known as CD289 or TLR9. CD289 is an 1032 amino acid ~120 kD endosomal single pass type I transmembrane glycoprotein with a number of and a single domain. Recognizes an epitope within the N-terminal (NT) region of CD289, a member of the toll-like receptor family, which triggers MyD88 and TRAF6, resulting in NF-kappaB activation, cytokine secretion and the inflammatory response. CD289 acts as a receptor for unmethylated cytidine-phosphate-guanosine dinucleotides in bacterial DNA (CpG-DNA), playing a primary role in pathogen recognition and activation of innate immunity and has been shown to play a role in defense against systemic mouse cytomegalovirus infection. Is reported as suitable for use in immunocytochemistry on acetone fixed cells.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa204-224
PresentationDesc :
PBS, 0.09% Sodium Azide, 0.1% BSA
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide LSLKYNNLTKVPRQLPPSLEY-C corresponding to amino acids 204-224 within the N-Terminus of mouse CD289. Percent identity by BLAST analysis: Mouse, Hamster (100%); Rat (95%); Panda, Dog, Cat, Horse, Guinea pig (90%); Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Ferret, Elephant, Pig (86%); Sheep, Goat, Zebu, Bovine, Rabbit (81%).
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG
Gene :
TLR9
StandardGeneSymbol :
TLR9
gene family :
Toll-like Receptor
Reactivity :
Mouse
Usage :
IHC-P (1:250), WB (1:1000)
ShortWebDescription :
TLR9 antibody LS-C187710 is an unconjugated goat polyclonal antibody to mouse TLR9 (aa204-224). Validated for IHC and WB.
Synonyms :
TLR9, CD289, CD289 antigen, Scri2a, Toll-like receptor 9
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.