This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CCR3 Antibody (aa5-28) LS-C187709
catalog :
LS-C187709
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry - paraffin section
product information
AntibodyID :
195612
AntibodyName :
LS-C187709
TargetSpecies :
Mouse
Host Species :
Goat
Product Name :
CCR3 Antibody (aa5-28) LS-C187709
Specificity :
Recognizes an epitope within the N-terminal (NT) region of mouse CD193, otherwise known as C-C chemokine receptor type 3 or CCR3. CD193 is a 359 amino acid ~42 kD multi pass transmembrane glycoprotein and member of the G-protein coupled receptor 1 family. CD193 is expressed by basophils, eosinophils, microglia, Th2 cells and dendritic cells. CD193 acts as a receptor for eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13) and RANTES (CCL5), the former being a chemoattractant for eosinophils and basophils. CD193 is involved in leukocyte chemotaxis and, along with CD191 (CCR1), is implicated as a regulator of T cell and dendritic cell interaction during the process of antigen presentation. CD193 is implicated as an activator of eosinophils in allergic lung disease, and is a useful TH2 cell marker in monitoring immune responses. Is reported as suitable for use in immunocytochemistry on acetone fixed cells.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa5-28
PresentationDesc :
PBS, 0.1% Sodium Azide, 0.1% BSA
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide TDEIKTVVESFETTPYEYEWAPPC corresponding to amino acids 5-28 within the N-Terminus of mouse CD193. Percent identity by BLAST analysis: Mouse (100%); Rat, Hamster (83%).
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG
Gene :
CCR3
StandardGeneSymbol :
CCR3
gene family :
GPCR
Subfamily :
Chemokine
Reactivity :
Mouse
Usage :
IHC-P (1:125), WB (1:500)
ShortWebDescription :
CCR3 antibody LS-C187709 is an unconjugated goat polyclonal antibody to mouse CCR3 (aa5-28). Validated for IHC and WB.
Synonyms :
CCR3, C-C chemokine receptor type 3, B-chemokine receptor, CD193, CD193 antigen, Chemokine c-c motif receptor 3, C-C chemokine receptor 3, CKR3, CC-CKR-3, CCR-3, CMKBR3, Eosinophil eotaxin receptor, Eotaxin receptor, C-C CKR-3, CC chemokine receptor 3
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.