This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CCR7 Antibody (aa2-22) LS-C187706
catalog :
LS-C187706
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, flow cytometry, immunohistochemistry - paraffin section
product information
AntibodyID :
195609
AntibodyName :
LS-C187706
TargetSpecies :
Mouse
Host Species :
Goat
Product Name :
CCR7 Antibody (aa2-22) LS-C187706
Specificity :
Recognizes mouse C-C chemokine receptor type 7, also known as CD197, CCR7, Epstein-Barr virus-induced G-protein coupled receptor 1 or MIP-3 beta receptor. CD197 is a 378 amino acid ~43 kD multi pass type III transmembrane glycoprotein and member of the G-protein coupled receptor 1 family. CD197 is expressed by various lymphoid tissues, activated B and T cells, naive T cells, NK cells and dendritic cells (DCs), which acts a high-affinity receptor for the chemokines MIP-3beta (CCL19) and CCL21. Ligand binding of CD197 plays a vital role in the homing of naive T cells and antigen-loaded DCs into secondary organs. Expression of CD197 is strongly up-regulated in B cells infected with Epstein-Barr virus (EBV) and T cells infected with herpesvirus 6 or 7. Can be used in research studies to distinguish between central memory and effector memory T cells and is reported as suitable for use in immunocytochemistry.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa2-22
PresentationDesc :
PBS, 0.1% Sodium Azide, 0.1% BSA
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide DPGKPRKNVLVVALLVIFQVC corresponding to amino acids 2-22 of mouse CD197. Percent identity by BLAST analysis: Mouse (100%); Rat, Hamster, Bovine (90%); Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (86%); Orangutan, Galago, Ferret, Dog, Cat, Horse (81%).
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG
Gene :
CCR7
StandardGeneSymbol :
CCR7
gene family :
GPCR
Subfamily :
Chemokine
Reactivity :
Mouse
Usage :
ELISA (1:100000), Flo (1:10), IHC-P (1:250), WB (1:1000)
ShortWebDescription :
CCR7 antibody LS-C187706 is an unconjugated goat polyclonal antibody to mouse CCR7 (aa2-22). Validated for ELISA, Flow, IHC and WB.
Synonyms :
CCR7, BLR2, Chemokine (C-C) receptor 7, CD197, C-C CKR-7, CMKBR7, CC chemokine receptor 7, CCR-7, CD197 antigen, CDw197, EBI1, EVI1, MIP-3 beta receptor, C-c chemokine receptor 7, C-C chemokine receptor type 7, CC-CKR-7, Chemokine c-c motif receptor 7
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.