This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
APP / Beta Amyloid Precursor Antibody (aa37-42, clone MAb1.1) LS-C187585
catalog :
LS-C187585
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MAb1.1

The same clone is also sold as:
reactivity :
human
application :
immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
AntibodyID :
195488
AntibodyName :
LS-C187585
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
APP / Beta Amyloid Precursor Antibody (aa37-42, clone MAb1.1) LS-C187585
Specificity :
Clone Mab1.1 recognizes Beta-amyloid protein 42 (also known as Abeta42), the 42 amino acid peptide processed from Amyloid precursor protein (APP). There are several forms of Abeta peptides processed from APP, the most common being Abeta40 and Abeta42. Amyloid plaques contain both Abeta40 and Abeta42. Abeta40 is more common, but Abeta42 more fibrillogenic and therefore associated with disease states such as Alzheimer's disease. Clone Mab1.1 specifically binds to the 37-42aa region, and does not recognize full-length APP or the 40 amino acid peptide processed from APP (Abeta40). It stains diffuse plaques found in the brain of Alzheimer's disease patients. It does not stain healthy brain tissue or other organs.
ClonalityDesc :
Monoclonal
CloneName :
MAb1.1
AntibodyModification :
Unconjugated
AntigenModification :
aa37-42
PresentationDesc :
PBS, 0.09% Sodium Azide
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
APP / Beta Amyloid Precursor
StandardGeneSymbol :
APP
gene family :
Amyloid precursor protein
Reactivity :
Human
Usage :
ELISA (0.2 µg/ml), IHC-Fr (20 - 40 µg/ml), IHC-P
ShortWebDescription :
Beta Amyloid Precursor antibody LS-C187585 is an unconjugated mouse monoclonal antibody to human Beta Amyloid Precursor (APP) (aa37-42). Validated for ELISA and IHC.
Synonyms :
APP, ABPP, A4, ABETA, AD1, Alzheimer disease, Amyloid beta, Beta-amyloid peptide, APPI, Beta amyloid, CVAP, AAA, PN2, PreA4, Amyloid beta A4 protein, Peptidase nexin-II, CTFgamma, PN-II, Protease nexin-II
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.