This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
SIGLEC7 / CD328 Antibody (clone S7.7, FITC) LS-C187562
catalog :
LS-C187562
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
S7.7

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
product information
AntibodyID :
195465
AntibodyName :
LS-C187562
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
SIGLEC7 / CD328 Antibody (clone S7.7, FITC) LS-C187562
Specificity :
Recognizes human Sialic acid-binding Ig-like lectin 7, otherwise known as CD328, a putative adhesion molecule and member of the Ig superfamily, predominantly expressed by both resting and activated natural killer (NK) cells, and also at lower levels by monocytes, granulocytes, monocyte-derived macrophages and dendritic cells, and a small population of CD8+ memory T cells. Classified as a CD33-related Siglec, Siglec-7 preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic acid, and acts as a novel inhibitory receptor for NK cells, mediating the inhibition of NK cell cytotoxicity, and implicated in the regulation of NK cell and T cell activation, and hematopoiesis. Clone S7.7 is a blocking antibody see for details, and has been shown to recognize Siglec-7 in Rhesus monkey see for details.
ClonalityDesc :
Monoclonal
CloneName :
S7.7
AntibodyModification :
FITC
PresentationDesc :
PBS, 0.09% Sodium Azide, 1% BSA
ImmunogenType :
Cells
ImmunogenDesc :
Siglec-7 3T3 transfected cells.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
SIGLEC7 / CD328
StandardGeneSymbol :
SIGLEC7
gene family :
Immunoglobulin
Reactivity :
Human
Usage :
Flo
ShortWebDescription :
CD328 antibody LS-C187562 is an FITC-conjugated mouse monoclonal antibody to human CD328 (SIGLEC7). Validated for Flow.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Synonyms :
SIGLEC7, AIRM-1, AIRM1, CD328 antigen, CDw328, CD328, D-siglec, QA79, SIGLEC-7, QA79 membrane protein
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.