This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
TNFRSF12A / TWEAK Receptor Antibody (clone ITEM-4, RPE) LS-C187520
catalog :
LS-C187520
clonality :
monoclonal
host :
mouse
conjugate :
RPE
clone name :
ITEM-4

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
product information
AntibodyID :
195423
AntibodyName :
LS-C187520
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
TNFRSF12A / TWEAK Receptor Antibody (clone ITEM-4, RPE) LS-C187520
Specificity :
Recognizes human CD266, otherwise known as Fn14/TWEAK Receptor, a 14kD type I transmembrane glycoprotein and member of the tumor necrosis factor receptor superfamily (TNFRSF12A) expressed by a variety of tissues, including the heart, lung and kidney, and at elevated levels by human brain and liver tumors. The interaction between CD266 and its ligand CD255 (TWEAK), induces the proliferation and migration of endothelial cells and also angiogenesis, and studies have shown that CD255-induced apoptosis of some tumor cell lines is mediated by CD266, see for details. Clone ITEM-4 is cross-reactive with mouse CD266, and also with Rat-1 cells in flow cytometry.
ClonalityDesc :
Monoclonal
CloneName :
ITEM-4
AntibodyModification :
RPE
PresentationDesc :
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
ImmunogenType :
Cells
ImmunogenDesc :
Human CD266 transfected P815 cells.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
ResuspensionLiquidDesc :
Reconstitute with distilled water.
IsotypeName :
IgG2b
Gene :
TNFRSF12A / TWEAK Receptor
StandardGeneSymbol :
TNFRSF12A
Reactivity :
Human
Usage :
Flo
ShortWebDescription :
TWEAK Receptor antibody LS-C187520 is an RPE-conjugated mouse monoclonal antibody to human TWEAK Receptor (TNFRSF12A). Validated for Flow.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Synonyms :
TNFRSF12A, CD266 antigen, CD266, FGF-inducible 14, FN14, Tweak-receptor, TWEAKR
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.