This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
SIRPA / CD172a Antibody (clone BL1H7) LS-C187488
catalog :
LS-C187488
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
BL1H7
reactivity :
human
application :
western blot, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
AntibodyID :
195391
AntibodyName :
LS-C187488
TargetSpecies :
Pig
Host Species :
Mouse
Product Name :
SIRPA / CD172a Antibody (clone BL1H7) LS-C187488
Specificity :
Porcine CD172a, a member of the signal regulatory protein (SIRP) family. Clone BL1H7 was originally clustered as SWC3 at the Third International Swine Cluster of Differentiation Workshop (;). CD172a is expressed on monocyte derived dendritic cells (MoDCs) also conventional (cDCs), plasmacytoid (pDCs) DCs and blood DCs.(; ). Clone BL1H7 immunoprecipitated a single band of ~90-110kD from preparations of biotinylated alveolar macrophages, a result confirmed by Western blotting analysis of alveolar macrophage lysates under non reducing conditions. Has proved a useful and reliable tool for immunohistochemical analysis of routinely processed, formalin fixed, paraffin embedded porcine tissues. Aberrant expression of CD172a has been noted on porcine leukemias with blast cells co-expressing lymphocytic markers CD5 and CD25 whilst expressing the Myeloid marker CD172a in a as opposed to the more characteristic of CD172+ cells seen in normal blood PBMC.
ClonalityDesc :
Monoclonal
CloneName :
BL1H7
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Cells
ImmunogenDesc :
Porcine alveolar macrophages.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
SIRPA / CD172a
StandardGeneSymbol :
SIRPA
Reactivity :
Pig
Usage :
Flo, IHC-Fr, IHC-P, IP, WB
ShortWebDescription :
CD172a antibody LS-C187488 is an unconjugated mouse monoclonal antibody to pig CD172a (SIRPA). Validated for Flow, IHC, IP and WB.
Synonyms :
SIRPA, CD172A, CD172a antigen, Inhibitory receptors shps-1, Inhibitory receptor SHPS-1, Macrophage fusion receptor, MyD-1 antigen, p84, SHPS-1, SHPS1, SIRP, Sirp-alpha-1, Sirp-alpha-3, Sirp-alpha1, MYD1, SIRPalpha, SIRPalpha2, BIT, MFR, MYD-1, PTPNS1, SHP substrate 1, Sirp-alpha-2, CD172
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.