product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
APP / Beta Amyloid Precursor Antibody (clone MOAB-2) LS-C181965
catalog :
LS-C181965
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MOAB-2
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 3
Reference
Frackowiak J, Mazur Kolecka B, Mehta P, Wegiel J. Enhanced accumulation of N-terminally truncated Aβ with and without pyroglutamate-11 modification in parvalbumin-expressing GABAergic neurons in idiopathic and dup15q11.2-q13 autism. Acta Neuropathol Commun. 2020;8:58 pubmed publisher
Kucheryavykh L, Kucheryavykh Y, Washington A, Inyushin M. Amyloid Beta Peptide Is Released during Thrombosis in the Skin. Int J Mol Sci. 2018;19: pubmed publisher
Kucheryavykh L, Dávila Rodríguez J, Rivera Aponte D, Zueva L, Washington A, Sanabria P, et al. Platelets are responsible for the accumulation of β-amyloid in blood clots inside and around blood vessels in mouse brain after thrombosis. Brain Res Bull. 2017;128:98-105 pubmed publisher
product information
AntibodyID :
189475
AntibodyName :
LS-C181965
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
APP / Beta Amyloid Precursor Antibody (clone MOAB-2) LS-C181965
Specificity :
Unaggregated, oligomeric and fibrillar forms of beta Amyloid 42 and unaggregated beta Amyloid 40. Does not detect APP.
ClonalityDesc :
Monoclonal
CloneName :
MOAB-2
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.05% Sodium Azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human beta Amyloid 42.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG2b
Gene :
APP / Beta Amyloid Precursor
StandardGeneSymbol :
APP
gene family :
Amyloid precursor protein
Reactivity :
Mouse, Rat, Human
Usage :
ICC, IHC, IHC-P (1:200 - 1:1000), WB
ShortWebDescription :
Beta Amyloid Precursor antibody LS-C181965 is an unconjugated mouse monoclonal antibody to Beta Amyloid Precursor (APP) from human. It is reactive with human, mouse and rat. Validated for ICC, IHC and WB. Cited in 2 publications.
Synonyms :
APP, ABPP, A4, ABETA, AD1, Alzheimer disease, Amyloid beta, Beta-amyloid peptide, APPI, Beta amyloid, CVAP, AAA, PN2, PreA4, Amyloid beta A4 protein, Peptidase nexin-II, CTFgamma, PN-II, Protease nexin-II
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.