product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
WWTR1 / TAZ Antibody (clone OTI1H9) LS-C173295
catalog :
LS-C173295
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OTI1H9
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 4
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:100; loading ...; fig 4b
  • immunohistochemistry; human; 1:50; loading ...; fig 2
Fullenkamp C, Hall S, Jaber O, Pakalniskis B, Savage E, Savage J, et al. TAZ and YAP are frequently activated oncoproteins in sarcomas. Oncotarget. 2016;7:30094-108 pubmed publisher
Szelachowska J, Donizy P, Ratajczak Wielgomas K, Halon A, Zielecka Debska D, Lichon K, et al. The effect of YAP expression in tumor cells and tumor stroma on the prognosis of patients with squamous cell carcinoma of the oral cavity floor and oral surface of the tongue. Oncol Lett. 2019;18:3561-3570 pubmed publisher
Merritt N, Fullenkamp C, Hall S, Qian Q, Desai C, Thomason J, et al. A comprehensive evaluation of Hippo pathway silencing in sarcomas. Oncotarget. 2018;9:31620-31636 pubmed publisher
Varzavand A, Hacker W, Ma D, Gibson Corley K, Hawayek M, Tayh O, et al. α3β1 Integrin Suppresses Prostate Cancer Metastasis via Regulation of the Hippo Pathway. Cancer Res. 2016;76:6577-6587 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-C173295 image 1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY WWTR1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-WWTR1.
image 2 :
LifeSpan Biosciences LS-C173295 image 2
IHC of paraffin-embedded Human breast tissue using anti-WWTR1 mouse monoclonal antibody.
product information
AntibodyID :
180719
AntibodyName :
LS-C173295
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
WWTR1 / TAZ Antibody (clone OTI1H9) LS-C173295
Specificity :
Human WWTR1
ClonalityDesc :
Monoclonal
CloneName :
OTI1H9
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol, 1% BSA
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Full length human recombinant protein of human WWTR1(NP_057287) produced in HEK293T cell.
PurificationDesc :
Protein A/G purified
RecommendedStorageDesc :
Store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG2a
Gene :
WWTR1 / TAZ
StandardGeneSymbol :
WWTR1
Reactivity :
Human
Usage :
IHC, IHC-P (1:150), WB (1:2000)
ShortWebDescription :
TAZ antibody LS-C173295 is an unconjugated mouse monoclonal antibody to human TAZ (WWTR1). Validated for IHC and WB. Cited in 4 publications.
Synonyms :
WWTR1
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.