This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
NOTCH1 Antibody (aa1754-1766) LS-C16929
catalog :
LS-C16929
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA
product information
AntibodyID :
17670
AntibodyName :
LS-C16929
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
NOTCH1 Antibody (aa1754-1766) LS-C16929
Specificity :
Recognizes human NOTCH 1. Species cross-reactivity: mouse Notch constructs present in lysates of HEK 293 cells. Only the cleaved intracellular (activated) form (NICD) is detected. Species sequence homology: mouse and rat NOTCH 1-100%. The epitope is only exposed after gamma secretase cleavage and is not accessible in the uncleaved form. No reactivity is detected against mouse N2, N3 or N4.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa1754-1766
PresentationDesc :
PBS, 0.1% Sodium Azide, 40% Glycerol, No stabilizing proteins added
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A synthetic peptide, VLLSRKRRRQHGQC, corresponding to amino acid residues 1755-1767 of human Notch 1. This is the N-Terminus sequence of the cleaved N intracellular domain (NICD). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Bovine, Dog, Horse (100%); Bat (92%); Opossum, Chicken, Trout, Stickleback (85%).
PurificationDesc :
Antiserum
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Gene :
NOTCH1
StandardGeneSymbol :
NOTCH1
Reactivity :
Mouse, Dog, Bovine, Rat, Hamster, Horse, Human, Monkey
Usage :
ELISA (1:10000 - 1:30000), WB (1:250)
ShortWebDescription :
NOTCH1 antibody LS-C16929 is an unconjugated rabbit polyclonal antibody to NOTCH1 (aa1754-1766) from human. It is reactive with human, mouse, rat and other species. Validated for ELISA and WB.
UsageText :
Suitable for use in ELISA and Western Blot. ELISA: 1:10000-1:30000. Standard sandwich ELISA using IgG, H&L (HRP) Pab Gt xRb. and ABTS as a substrate for 30 minutes at RT. Western Blot: 1:250. Against recombinant mouse Notch constructs in 293 cells. An 80kD band corresponding to Notch 1.
Synonyms :
NOTCH1, Notch 1, TAN1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.