product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
ABCC3 / MRP3 Antibody (aa830-949) LS-C16477
catalog :
LS-C16477
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
citations: 1
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human
Kleberg K, Jensen G, Christensen D, Lundh M, Grunnet L, Knuhtsen S, et al. Transporter function and cyclic AMP turnover in normal colonic mucosa from patients with and without colorectal neoplasia. BMC Gastroenterol. 2012;12:78 pubmed
product information
AntibodyID :
17218
AntibodyName :
LS-C16477
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
ABCC3 / MRP3 Antibody (aa830-949) LS-C16477
Specificity :
Recognizes an internal epitope of human MRP3. Does not cross-react with human P-glycoprotein, MDR3 P-glycoprotein, MRP1, MRP2 (cMOAT) or MRP5. Does not cross-react with mouse, rat or guinea pig MRP2.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa830-949
PresentationDesc :
Tissue Culture Supernatant, 0.09% Sodium Azide, 0.07% BSA
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human MRP3 (multidrug resistance-associated protein 3) (aa 830-949).
PurificationDesc :
Tissue culture supernatant
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
ABCC3 / MRP3
StandardGeneSymbol :
ABCC3
gene family :
Transporter
Subfamily :
ATP-binding cassette - ABCC/MRP
Reactivity :
Human
Usage :
ELISA, Flo, ICC (1:20 - 1:50), IF, IHC, IHC-Fr, WB (1:20 - 1:50)
ShortWebDescription :
MRP3 antibody LS-C16477 is an unconjugated mouse monoclonal antibody to human MRP3 (ABCC3) (aa830-949). Validated for ELISA, Flow, ICC, IF, IHC and WB. Cited in 1 publication.
UsageText :
Suitable for use in Immunofluorescence, Flow Cytometry, ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Flow Cytometry: Weak, cell permeabilization required. Western Blot: Use 1:20-1:50 and IgG (HRP) anti-mouse. Immunocytochemistry: 1:20-1:50 on acetone or formaldehyde fixed cytospin preparations. Immunohistochemistry (Frozen sections): 1:20 on acetone fixed frozen sections followed by incubation with IgG rabbit anti-mouse and a monoclonal mouse APAAP complex. Alternatively, after incubation with the primary antibody (1:20) and washing, slides can be incubated with IgG (Biotin) rabbit anti-mouse and Streptavidin (HRP).
Synonyms :
ABCC3, ABC31, EST90757, MOAT-D, MLP2, Multidrug resistance protein 3, MRP3, CMOAT2
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.