product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
Integrin Alpha V Beta 3 Antibody (Biotin) LS-C15967
catalog :
LS-C15967
clonality :
monoclonal
host :
mouse
conjugate :
biotin
reactivity :
human, dogs
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
LifeSpan Biosciences product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • western blot; dogs; loading ...; fig s6b
Zhang K, Myllymäki S, Gao P, Devarajan R, Kytölä V, Nykter M, et al. Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with αV-Class integrins to promote EMT. Oncogene. 2017;36:5681-5694 pubmed publisher
Teräväinen T, Myllymäki S, Friedrichs J, Strohmeyer N, Moyano J, Wu C, et al. ?V-integrins are required for mechanotransduction in MDCK epithelial cells. PLoS ONE. 2013;8:e71485 pubmed publisher
product information
AntibodyID :
16708
AntibodyName :
LS-C15967
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
Integrin Alpha V Beta 3 Antibody (Biotin) LS-C15967
Specificity :
Recognizes the human vitronectin receptor aVb3 complex, an RGD-directed adhesion receptor. Species cross-reactivity: bovine, chicken, monkey, porcine, canine, rabbit and avian. Not reactive with rat tissue.
ClonalityDesc :
Monoclonal
AntibodyModification :
Biotin
PresentationDesc :
PBS, pH 7.1, 15 mg/ml BSA, 0.1% Sodium Azide
ImmunogenType :
Cells
ImmunogenDesc :
Purified adhesion receptor from the human melanoma cell line M21.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
Integrin Alpha V Beta 3
Reactivity :
Chicken, Bovine, Rabbit, Dog, Pig, Human, Monkey
Usage :
Func, IF, IP
UsageNotRecommended :
IHC-P
ShortWebDescription :
Integrin Alpha V Beta 3 antibody LS-C15967 is a biotin-conjugated mouse monoclonal antibody to Integrin Alpha V Beta 3 from human. It is reactive with human, bovine, chicken and other species. Validated for Func, IF and IP. Cited in 1 publication.
UsageText :
Suitable for use in Immunoprecipitation, Immunofluorescence,. and Inhibition. Not suitable for immunohistochemical staining of paraffin-embedded tissue sections. Inhibition: Inhibits adhesion of cells to vitronectin coated surfaces at 10-25 ug/ml. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.